The front lines of information security will not include humans. As defenses continue to succumb to an endless barrage of attacks and an almost immeasurable onslaught of new attack techniques, the notion of humans being able to deploy detection technologies and choreograph responses in real-time will fall away. In essence, human interaction with cyber defense will be deemed for what it currently is –imperfect and unreliable in the face of attacks that are largely automated and mostly reliable, if not perfect. It will be the fall of human cyber defenses and the rise of the cyber botted-defenses.