The first tim I bought Bitcoin on Coinbase I immediately sent it out to Bittrex to start trading with. It was only $200 worth, but I had never transferred anything on the blockchain before so I was super nervous. Did I get the address right? Did I send to the right address? How do I know if it goes through? I’m freaking out a little and it took 30 minutes for the transaction to go through! Being used to instant transactions I went through all the stages of grief and just as I had reconciled myself to the fact I had lost my money, it showed up on Bittrex! That was the most stressful 30 minutes of my life! Thanks for the post @knircky!
Note that Coinbase doesn't necessarily create a transaction immediately with your withdrawal. So some of the delay could be waiting for the bank to actually broadcast the withdrawal.