Parkinson's disease
Read Montague in Virginia Tech Carilion Research Institute due to the loss of dopamine-producing brain cells
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As a result of an experiment in patients with Parkinson's disease, he said the following. We saw that dopamine followed two factors: what happened and what could have happened. Our dopamine neurons monitor whether something can be better or worse, and this information is coded by rapid changes in dopamine release.
For awards, it is called the reward estimation errors.
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Specifically this award provides a learning signal to guide future behaviors in estimating errors. Eric Bowman, a neurophysiologist, says that it is very unlikely that we will be aware of the actions we have been committed to, but unconsciously cause dopamine activation, and this lack of awareness may explain why people make apparently unreasonable or unfair choices.
For example smoking. The nicotine in cigarette has been added to receptors in the mesolimbic reward system and plays a central role in tobacco dependence. It explains why it is so consumed. Addiction in the language of the people is the action of dopamine activity and they are very motivated.
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