While I do think that some big Youtubers will come over to Dtube, I fear that there currently aren't enough features and too many bugs for them to make Dtube their primary platform.

The Amazing Atheist (@tjkirk) made a post a couple of days ago where he talked about some of the problems he's having with Dtube. Definitely worth a read.

Source: https://steemit.com/dtube/@tjkirk/dtube-s-fatal-flaw