The traditional texts designate Cow Ghee as Medhya Rasayana, beneficial for mental alertness and memory. There has been concern about increased risk of cardiovascular disease due to its high percentage of saturated fatty acids in ghee.

Cow ghee enhances the availability of enzymes responsible for detoxification of cancer-causing substances and decreases the availability of those responsible for activation of carcinogens, scientists from the National Dairy Research Institute (NDRI).

Cow ghee and butter group showed no significant effect on memory in EPM and MWM model. There was reduction in weight of animals in Cow Ghee group and increase in weight with Butter.Being pure, clarified butter, ghee is extremely rich in good fats. One serving (56 grams) of ghee contains 46 grams of pure fat, of which 29 grams are saturated. Moreover, these fats contain 179 milligrams of omega-3 fatty acids and 1,548 milligrams of omega-6 fatty acids.

One serving of ghee contains approximately 1,418 IU of vitamin A, which is 28 percent of our recommended daily intake. Vitamin A, which is lacking in other edible oils, is nicknamed the "medicine of the immune system".

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