This post is showing the sodium transport coupled with the transport of dicarboxylates in the apical and basolateral membranes of the S1 segment of the proximal tubule.

• The Na/K ATPase, which brings 2 potassium ions into the cell and releases 3 sodium ions into the interstitial space.
• The sodium/dicarboxylate cotransporter (NaDC1) at the apical membrane, which brings in 3 sodium ions from the filtrate together with 1 dicarboxylate ion which could be citrate, α keto-glutarate or succinate.
• The sodium/dicarboxylate cotransporter (NaDC3) at the basolateral membrane, which brings in 3 sodium ions from the interstitium and brings in mainly α keto-glutarate. This transporter is important for the organic anion transport which will be shown at a later post

Previous Posts in this Series

Renal Tubular Transport #1. S1 Segment, Proximal Tubule. Sodium Transport 1

Renal Tubular Transport #2. S1 Segment, Proximal Tubule. Sodium Transport 2

Renal Tubular Transport #3. S1 Segment, Proximal Tubule. Sodium Transport 3

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