It was in 1947 that Isaac Karlin suggested that stuttering was caused by "delay in the myelinization of the cortical areas in the brain concerned with speech." In 1988, research by Dietrich and others using MRI imaging of the brains of infants and children from four days old to 36 months of age have found that those that were developmentally delayed had immature and disrupted patterns of myelination.

Propitiously, it has been found that impairment of these developmental processes in myellination also alters neural communications without necessarily causing severe neural damage and while not presenting a medically diagnosed problem. These facts have been adequately proven by science, but ignored and suppressed by mainstream medical establishment.