Yes, the crisis is the worst complication and treatment symptomatic, pain relief, much to drink to make blood flow. Giving massage is good with the hope that the blood cells due to widening of vessels and good blood flow come apart and the vessels will be free. I think this is for children the best option.

In rarely cases people need blood transfusion or blood filter. Luckily many nowadays diagnose early and will know what to do if the first symptom come.