Heart Rate and Rhythm and the Benefit of Beta-Blockers in Patients With Heart Failure@JACC
【I will translate famous articles from original to Japanese in this series】
心不全患者における心拍数および調律とβ遮断薬の有益性
Background The relationship between mortality and heart rate remains unclear for patients with heart failure with reduced ejection fraction in either sinus rhythm or atrial fibrillation (AF).
背景
洞調律または心房細動（AF）のいずれかにあり、駆出分画が低下した心不全患者における死亡率と心拍数の関係は明らかになっていない。
Objectives This analysis explored the prognostic importance of heart rate in patients with heart failure with reduced ejection fraction in randomized controlled trials comparing beta-blockers and placebo.
目的
本解析は、β遮断薬とプラセボを比較する無作為化対照試験を対象とし、駆出分画が低下した心不全患者において心拍数が持つ予後予測上の重要性を明らかにすることを目的とした。
Methods The Beta-Blockers in Heart Failure Collaborative Group performed a meta-analysis of harmonized individual patient data from 11 double-blind randomized controlled trials.
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