Yes - such advancements are possible without technology, though still have limitations. For such technological advancements to be utilized constructively would most likely require such internal development of natural intelligence, first - in order to develop the wisdom to effectively manage the power such external technologies would enable.

Both Limitless & Lucy - AMAZING movies. not entirely fiction. Both present a fairly accurate representation of what may be possible with the development of the brain. and anyone who's done psychedelics may be familiar with these states. (there's probably good reason the movie was called "Lucy.") though even the psychedelic experiences aren't just because of the drugs themselves - the compounds are just a high-energy fuel source to activate increased brain processing power, unveiling the potential of human consciousness. such states ARE possible without external substances - the brain produces DMT naturally, and if one knows how, DMT can be produced intentionally in higher-than-normal doses.

very exciting times and things ahead, with such developments in all these fields...