I take tricyclic antidepressants, anafranil/chlompramine since SSRIs were not so helpful. They do not elliminate anxiety/depression entirely but its much more manageable. SSRIs have different side-effects, especially increasing anxiety and insomnia before they begin to work that's why I prefer tricyclics. SSRIs are overrated and Tricyclics underrated and underestimated but ok, if you found zoloft to be helpful, I am really glad. There are many good reviews and testimonies when it comes to zoloft in comparison to other SSRIs.