I would pop a Dramamine about 40 minutes before boarding not cuz I might get air sick but it knocks my lights out or relaxes me. I also have nice canceling headphones so the screaming /crying baby syndrome goes bye bye too. I always choose the window seat. Luckily I'm not a big person. One tip you may want to do is when you book a flight, find out what type of plne you will be and the airline. Then open a new tab and do a google search for the plane, airline, and seating chart. Some website have reviews of the seat you are booking which may help.