Research

In the study, it was observed that the mice kept in an isolated environment for two weeks showed aggressive, stubborn, cowardly behaviors against the mice they met and hypersensitivity to threatening stimuli.

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That is, many behavioral changes were observed in long-isolated isolated mice. The behavioral changes mentioned here mean increased aggression, constant fear and extreme sensitivity to stimuli.

In a previous study of the same team with fruit flies, a special neurochemistry called tachykinin was found to play a role in the increase of aggression in isolated fruit flies. Tachykinin is a neuropeptide, a short protein molecule that is released from certain nerve cells.

Neuropeptides bind to specific receptors in other nerve cells, altering the physiological properties of these nerve cells and affecting the neural circuit function of the nerve cell. The team, which continues to work with mice, found that the mouse tachykinin gene (Tac2) encodes a neuropeptide called neurokinin (NkB).

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NkB is produced by neurons in specific regions of the mouse brain (in the amygdala and hypothalamus, which play a role in emotional and social behavior).

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