Immunology question game! Give me your best answers. (Round 2)

Hey steemit community, think you know immunology? Provide your best answers to these questions and we'll see whose answers get up-voted the most. I'll provide feedback to your answers and we'll see how well we can

Q1: Commensal bacteria live on our bodies (e.g. on skin) and in our bodies (e.g. mucosal surfaces). These bacteria typically do not cause pathology. When might they cause pathology and why? (Hint: Location, location, location…)

Q2: The “3 Big Challenges” of immunity are specificity, tolerance, and appropriateness. The final challenge hints that immune responses can vary depending on the nature of the problem. Discuss the lifestyle differences of various infectious diseases. What T cell type is associated with intracellular pathogens? Extracellular pathogens? (Warning: There are many caveats and exceptions to these T cell/pathogen associations.)

Q3: Taking a step back, we will take a look at tolerance, the ability of the immune system to ignore non-dangerous commensal organisms and, perhaps more importantly, the body of the organism with the immune system. Discuss the “Danger Hypothesis”.

Q4: Compare and contrast innate and adaptive immunity. Which branch commonly uses receptors encoded in the germline? Receptors that are randomly generated?

Q5: How is adaptive immunity linked to immunological memory? What does this have to do with vaccines?

Q6: Discuss the following:
-Hypersensitivity reactions
-Autoimmune diseases
-Immune deficiency

Q7: Compare and contrast immune responses to cancer and to transplanted organs. What is the cause of immunodeficiency in these two different situations?