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RE: All about the Sperm-DNA (My Research, Vol. 1)
@suesa can you clarify this sentence "During the first few hours after fertilization, paternal and maternal DNA seem to “increase in size”"
It wasn't clear if it was before the sperm and egg pronuclei fuse or it after the pronuclei fuse to form the one cell zygote?
Cheers!
Ian
It's before the pronuclei fuse :) when I was talking about "paternal and maternal DNA" what I meant was "pronuclei". But when writing a post for non-scientists, I try to keep the amount of scientific words low.
Thanks for the clarification, that is what I had thought. Here is a link to an interesting article on hydroxymethylation and how it regulates retinal neurogenesis in a cell non-autonomous way by regulating Wnt and Notch pathways in zebrafish. You may have already seen it, but thought it may provide some mechanistic insight to what is going on with the paternal DNA during fertilization. https://www.ncbi.nlm.nih.gov/pubmed/28926578
Cheers!
Thanks!