Well, yes, much of this is beyond me and suited for someone who works in a research/laboratory setting. Still, a reading of your blog allows me to, in a sense "look behind the curtain", to get an idea of what is entailed when we submit tissue for lab analysis. I can think of a number of times when I've had lab tests done and the doctor has dismissed the results as unlikely, or unreliable. And sometimes, the report comes back and declares that the original sample, submitted for testing, was somehow unreliable.
With all the variables you describe in technique/procedure, I can see why this unreliability may exist.
I admire your knowledge :)