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RE: Stopping Post Surgical Infections With Small Pieces of Protein (Peptides)
There are a lot of problems at the moment. They do aggregate, are chemically and physically unstable, have short half-lives in plasma. While their antibiotic activity is top notch and is improving, now is full of engineering problems.
Fosgerau, K., & Hoffmann, T. (2015). Peptide therapeutics: current status and future directions. Drug Discovery Today, 20(1), 122–128. https://doi.org/10.1016/j.drudis.2014.10.003
Engineering problem is something we would always have. Thanks for the link.