The first Buddha sat under the Bodhi tree and meditated. He went through all of his lives, both forwards and backwards, and found that there is no I. (This isn't something you get intellectually, this is a thing you will have to experience for yourself. And it is not an easy path.)

Science likes to cut things apart. (Science derives from the same roots as scythe, and means to cut)
To a scientist there is physics, which deals with all of the physical things, and metaphysics where all the woowoo stuff happens, and we won't ever discuss that stuff.

But, physics and metaphysics are more of a continuum. There is no nice solid break.
And so, by leaving metaphysics out of science, all of science is wrong.